Composite Angioimmunoblastic T-Cell Lymphoma and Diffuse Large B-Cell Lymphoma

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Diffuse large B-cell lymphoma in patient after treatment of angioimmunoblastic T-cell lymphoma.

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Angioimmunoblastic T-cell lymphoma

The lymphoma cell is a peripheral T lymphocyte in various stages of differentiation. The neoplastic clone expresses T-cell antigens and is usually CD4+. The malignant T-cells are believed to secrete cytokines responsible for the polyclonal B-cell hyperplasia observed in involved nodes. Clonality studies demonstrated a monoclonal rearrangement of the bchain of the T-cell receptor (TCR) in the ma...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 2002

ISSN: 0002-9173,1943-7722

DOI: 10.1309/vd2d-98me-mb3f-wh34